Package: upndown Type: Package Title: Utilities and Design Aids for Up-and-Down Dose-Finding Studies Version: 0.4.0 Date: 2025-12-30 Description: Up-and-Down (UD) is the most popular design approach for dose-finding, but it has been severely under-served by the statistical and computing communities. This is the first package that comprehensively addresses UD's needs. Development version available on Github: assaforon/upndown. Recent applied UD tutorial: Oron et al., 2022 . Recent methodological overview: Oron and Flournoy, 2024 . License: GPL-2 Authors@R: person('Assaf P.','Oron', role=c('cre','aut'), email='assaf.oron@gmail.com') RoxygenNote: 7.3.2 Roxygen: list(markdown = TRUE) Encoding: UTF-8 Suggests: knitr, rmarkdown Imports: cir, expm, MASS, plyr VignetteBuilder: knitr Repository: https://assaforon.r-universe.dev Date/Publication: 2025-10-26 01:21:03 UTC RemoteUrl: https://github.com/assaforon/upndown RemoteRef: HEAD RemoteSha: 97293500f33e8da050e0e3f0292595aaa39ce992 NeedsCompilation: no Packaged: 2026-10-10 09:01:24 UTC; root Author: Assaf P. Oron [cre, aut] Maintainer: Assaf P. Oron